Optimizing the management of Guillain-Barré syndrome

Résumé

This book offers a structured overview of Guillain-Barré syndrome, now the leading cause of acute flaccid paralysis after the near-eradication of poliomyelitis. It reviews epidemiology, immune pathophysiology, typical clinical presentation, variants, and the main diagnostic and differential-diagnostic tools. It also examines disease chronology, prognostic factors, and triggers, especially infections. A substantial part of the book is devoted to therapeutic management, from intravenous immunoglobulins and plasma exchange to intensive care, rehabilitation, and post-acute follow-up. The overall approach is multidisciplinary, emphasizing early reassessment, prevention of complications, functional recovery, and long-term patient outcomes with practical attention to severity, monitoring, and quality of life.