Academic publication

Bioavailability of Bunium incrassatum L.

MEKRAF Souheyla

Bibliographic information

Publication date
2026-09-01
Language
Anglais
ISBN
978-9969-677-91-1
Pages
98
Format
16 × 24 cm
Subject Area
Sciences de la Nature et de la Vie

Keywords

Bunium incrassatum · bioavailability · medicinal plants · phytochemistry · polyphenols

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Internal editorial assessment

Abstract

This book explores the therapeutic potential of Bunium incrassatum L. (Talghouda), a North African medicinal plant rich in bioactive polyphenols. Methanolic extracts from seeds, roots, and stems were chemically characterized and evaluated for antioxidant and cholesterol-gallstone-dissolving activities. Seed extract showed the highest phenolic content and strong antioxidant performance, while all extracts demonstrated litholytic potential. In vivo experiments further showed that seed extract reduced thyroxine-induced hyperthyroidism in rats by improving T3, T4, and TSH levels and partially protecting thyroid tissue. The findings highlight B. incrassatum as a promising source of therapeutic compounds while emphasizing the need for further pharmacokinetic and clinical studies.

Authors and contributors

MEKRAF Souheyla

Suggested citation

MEKRAF Souheyla. Bioavailability of Bunium incrassatum L.. SARAHMED Éditions, 2026. ISBN : 978-9969-677-91-1

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